RT Journal Article SR Electronic T1 Patients' views of antidepressants: from first experiences to becoming expert JF British Journal of General Practice JO Br J Gen Pract FD British Journal of General Practice SP e142 OP e148 DO 10.3399/bjgp11X567045 VO 61 IS 585 A1 Peter Schofield A1 Ann Crosland A1 Waquas Waheed A1 Saadia Aseem A1 Linda Gask A1 Annie Wallace A1 April Dickens A1 André Tylee YR 2011 UL http://bjgp.org/content/61/585/e142.abstract AB Background The majority of patients discontinue antidepressant treatment earlier than prescribed. The factors behind this and the influences on patients' choices about whether to take medication remain poorly understood.Aim To explore factors that influence patients' decisions about taking antidepressant medication.Design of study Qualitative interview study.Setting Interviews were conducted across three sites: London, East Lancashire, and North East England.Method Semi-structured interviews were conducted with a purposive sample of 65 primary care patients who were prescribed antidepressants in the past year for depression or mixed anxiety/depression.Results Participants described their first course of antidepressants as typically occurring when they had ‘hit rock bottom’, having exhausted all other possibilities; therefore, there was little sense of a positive choice at this stage. There would typically follow a period of experimentation where it was usual to stop and restart medication, often several times. Ultimately, these recurring cycles lead to participants becoming more expert about their condition and better able to make an informed decision about medication. For younger participants, recovery typically remained a goal, although for older people there was often an acceptance that their condition, and medication use, would be long term.Conclusion Participants' accounts demonstrated how they could become expert at managing their condition through a process of trial and error.