PT  - JOURNAL ARTICLE
AU  - Daniel Chandler
AU  - Martin Connor
AU  - David Breen
TI  - Hib epiglottitis despite fully vaccinated status
AID  - 10.3399/bjgp09X453828
DP  - 2009 Aug 01
TA  - British Journal of General Practice
PG  - 597--598
VI  - 59
IP  - 565
4099  - http://bjgp.org/content/59/565/597.short
4100  - http://bjgp.org/content/59/565/597.full
SO  - Br J Gen Pract2009 Aug 01; 59
AB  - The introduction of an effective vaccine has markedly reduced the incidence of invasive Haemophilus influenzae type b (Hib) disease. However, vaccination failure can occur, and this report describes one such case in a previously healthy 4-year-old girl, who became severely unwell with Hib epiglottitis. She had received a full course of Hib vaccine administered via the buttocks. This site has been associated with reduced immunogenicity compared to vaccination by injection into the thigh or deltoid muscles. Current recommendations are to avoid gluteal injection for all vaccinations.