TY - JOUR T1 - Significant Events JF - British Journal of General Practice JO - Br J Gen Pract SP - 403 LP - 403 DO - 10.3399/bjgp11X578061 VL - 61 IS - 587 AU - David Jewell Y1 - 2011/06/01 UR - http://bjgp.org/content/61/587/403.abstract N2 - I had a Significant Event recently. Not, you understand, a real significant event such as a bereavement or a son getting married; but a Significant Event involving a Patient. You know — the kind we make notes on and proudly enter in our appraisal portfolios. The Event was the discovery that a patient’s mild but long-standing anaemia was almost certainly a side effect of treatment with carbamazepine. Not that significant (although finding that I had made the same discovery a couple of years ago and forgotten did make it moderately Significant for me personally), but it did set me thinking.The thinking concerned side effects of drugs. The most widely quoted evidence about such effects comes from data on patients admitted to US hospitals.1 Up till now I have tended to think that such data doesn’t apply to UK primary care. But then I used … ER -