RT Journal Article SR Electronic T1 Reducing antibiotic prescribing for children with respiratory tract infections in primary care: a systematic review JF British Journal of General Practice JO Br J Gen Pract FD British Journal of General Practice SP e445 OP e454 DO 10.3399/bjgp13X669167 VO 63 IS 612 A1 Talley A Vodicka A1 Matthew Thompson A1 Patricia Lucas A1 Carl Heneghan A1 Peter S Blair A1 David I Buckley A1 Niamh Redmond A1 Alastair D Hay A1 , YR 2013 UL http://bjgp.org/content/63/612/e445.abstract AB Background Respiratory tract infections (RTIs) in children are common and often result in antibiotic prescription despite their typically self-limiting course.Aim To assess the effectiveness of primary care based interventions to reduce antibiotic prescribing for children with RTIs.Design and setting Systematic review.Method MEDLINE®, Embase, CINAHL®, PsycINFO, and the Cochrane library were searched for randomised, cluster randomised, and non-randomised studies testing educational and/or behavioural interventions to change antibiotic prescribing for children (<18 years) with RTIs. Main outcomes included change in proportion of total antibiotic prescribing or change in ‘appropriate’ prescribing for RTIs. Narrative analysis of included studies was used to identify components of effective interventions.Results Of 6301 references identified through database searching, 17 studies were included. Interventions that combined parent education with clinician behaviour change decreased antibiotic prescribing rates by between 6–21%; structuring the parent–clinician interaction during the consultation may further increase the effectiveness of these interventions. Automatic computerised prescribing prompts increased prescribing appropriateness, while passive information, in the form of waiting room educational materials, yielded no benefit.Conclusion Conflicting evidence from the included studies found that interventions directed towards parents and/or clinicians can reduce rates of antibiotic prescribing. The most effective interventions target both parents and clinicians during consultations, provide automatic prescribing prompts, and promote clinician leadership in the intervention design.