TY - JOUR T1 - The prevalence and nature of prescribing and monitoring errors in English general practice: a retrospective case note review JF - British Journal of General Practice JO - Br J Gen Pract SP - e543 LP - e553 DO - 10.3399/bjgp13X670679 VL - 63 IS - 613 AU - Anthony J Avery AU - Maisoon Ghaleb AU - Nick Barber AU - Bryony Dean Franklin AU - Sarah J Armstrong AU - Brian Serumaga AU - Soraya Dhillon AU - Anette Freyer AU - Rachel Howard AU - Olanrewaju Talabi AU - Rajnikant L Mehta Y1 - 2013/08/01 UR - http://bjgp.org/content/63/613/e543.abstract N2 - Background Relatively little is known about prescribing errors in general practice, or the factors associated with error.Aim To determine the prevalence and nature of prescribing and monitoring errors in general practices in England.Design and setting Retrospective case-note review of unique medication items prescribed over a 12-month period to a 2% random sample of patients. Fifteen general practices across three primary care trusts in England.Method A total of 6048 unique prescription items prescribed over the previous 12 months for 1777 patients were examined. The data were analysed by mixed effects logistic regression. The main outcome measures were prevalence of prescribing and monitoring errors, and severity of errors, using validated definitions.Results Prescribing and/or monitoring errors were detected in 4.9% (296/6048) of all prescription items (95% confidence interval [CI] = 4.4% to 5.5%). The vast majority of errors were of mild to moderate severity, with 0.2% (11/6048) of items having a severe error. After adjusting for covariates, patient-related factors associated with an increased risk of prescribing and/or monitoring errors were: age <15 years (odds ratio [OR] = 1.87, 95% CI = 1.19 to 2.94, P = 0.006) or >64 years (OR = 1.68, 95% CI = 1.04 to 2.73, P = 0.035), and higher numbers of unique medication items prescribed (OR = 1.16, 95% CI = 1.12 to 1.19, P<0.001).Conclusion Prescribing and monitoring errors are common in English general practice, although severe errors are unusual. Many factors increase the risk of error. Having identified the most common and important errors, and the factors associated with these, strategies to prevent future errors should be developed, based on the study findings. ER -