RT Journal Article SR Electronic T1 Improving anticoagulation in atrial fibrillation: observational study in three primary care trusts JF British Journal of General Practice JO Br J Gen Pract FD British Journal of General Practice SP e275 OP e281 DO 10.3399/bjgp14X679705 VO 64 IS 622 A1 John Robson A1 Isabel Dostal A1 Rohini Mathur A1 Ratna Sohanpal A1 Sally Hull A1 Sotiris Antoniou A1 Peter MacCallum A1 Richard Schilling A1 Luis Ayerbe A1 Kambiz Boomla YR 2014 UL http://bjgp.org/content/64/622/e275.abstract AB Background Atrial fibrillation (AF) is a cause of stroke, and undertreatment with anticoagulants is a persistent issue despite their effectiveness.Aim To increase the proportion of people with AF treated appropriately using anticoagulants, and reduce inappropriate antiplatelet therapy.Design of study Cross-sectional analysis.Setting Electronic patient health records on 4604 patients with AF obtained from general practices in three inner London primary care trusts between April 2011 and 2013.Method The Anticoagulant Programme East London (APEL) sought to achieve its aims through an intervention with three components: altering professional beliefs using new clinical guidance and related education; facilitating change using computer software to support clinical decisions and patient review optimising anticoagulation; motivating change through evaluative feedback showing individual practice performance relative to peers.Results From April 2011 to April 2013, the proportion of people with CHA2DS2-VASc ≥1 on anticoagulants increased from 52.6% to 59.8% (trend difference P<0.001). The proportion of people with CHA2DS2-VASc ≥1 on aspirin declined from 37.7% to 30.3% (trend difference P<0.001). Comparing the 2 years before the intervention with the 2 years after, numbers of new people on the AF register almost doubled from 108 to 204.Conclusions The APEL programme supports improvement in clinical managing AF by a combined programme of education around agreed guidance, computer aids to facilitate decision-making and patient review and feedback of locally identifiable results. If replicated nationally over 3 years, such a programme could result in approximately 1600 fewer strokes every year.