TY - JOUR T1 - The chronotherapy of hypertension: or the benefit of taking blood pressure tablets at bedtime JF - British Journal of General Practice JO - Br J Gen Pract SP - 171 LP - 171 DO - 10.3399/bjgp17X690269 VL - 67 IS - 657 AU - Gervase Vernon Y1 - 2017/04/01 UR - http://bjgp.org/content/67/657/171.abstract N2 - The chronotherapy of hypertension is a relatively new practice in the UK. Yet the latest RCT (MAPEC)1 shows that taking blood pressure (BP) tablets at bedtime instead of in the morning (for those of our patients who are on more than one BP tablet per day) lowers the night-time blood pressure and reduces the relative risk of major cardiovascular disease (CVD) events by about 60% (P = 0.33) over 5 years.2This translates (very roughly) into a number needed to treat (NNT) of 300 to … ER -