TY - JOUR T1 - Chest discomfort at night and risk of acute coronary syndrome: cross-sectional study of telephone conversations JF - British Journal of General Practice JO - Br J Gen Pract DO - 10.3399/bjgp20X711317 VL - 70 IS - suppl 1 SP - bjgp20X711317 AU - Loes Wouters AU - Dorien Zwart AU - Carmen Erkelens AU - Esther de Groot AU - Roger Damoiseaux AU - Arno Hoes AU - Frans Rutten Y1 - 2020/06/01 UR - http://bjgp.org/content/70/suppl_1/bjgp20X711317.abstract N2 - Background During telephone triage it is difficult to assign the adequate urgency to patients with chest discomfort. Considering the time of calling could be helpful.Aim To assess the risk of acute coronary syndrome (ACS) in certain time periods and whether sex influences this risk.Method Cross-sectional study of 1,655 recordings of telephone conversations of patients who called the out-of-hours services primary care (OHS-PC) for chest discomfort. Call time, patient characteristics, symptoms, medical history and urgency allocation of the triage conversations were collected. The final diagnosis of each call was retrieved at the patient’s general practice. Absolute numbers of patients with and without ACS were plotted and risks per hour were calculated. The risk ratio of ACS at night (0 am to 9 am) was calculated by comparing to the risk at other hours, and was adjusted for gender and age.Results The mean age of callers was 58.9 (SD ± 19.5) years, 55.5% were women and in total, 199 (12.0%) had an ACS. The crude risk ratio for an ACS at night was 1.80 (CI = 1.39 to 2.34, P<0.001); 2.33 (1.68 to 3.22, P<0.001) for men, and 1.29 (0.83 to 1.99, P = 0.256) for women. The adjusted risk ratio for ACS of all people at night was 1.82 (1.07 to 3.10, P = 0.039).Conclusion Patients calling the OHS-PC for chest discomfort between 0–9 am have almost twice a higher risk of ACS than those calling other hours, a phenomenon more evident in men than in women. At night, dispatching ambulances more ‘straightaway’ could be considered for these patients with chest discomfort. ER -