TY - JOUR T1 - Morbidity and drugs in pregnancy JF - The Journal of the Royal College of General Practitioners JO - J R Coll Gen Pract SP - 631 LP - 645 VL - 25 IS - 158 AU - The Birmingham Research Unit of the Royal College of General Practitioners Y1 - 1975/09/01 UR - http://bjgp.org/content/25/158/631.abstract N2 - In a prospective study involving 9,000 pregnant women, no cause-and-effect relationships have been established between morbidity recorded or drugs taken during early pregnancy and subsequent congenital malformations. The relationships that have been identified are largely explained by the influence of a history of a previous abnormal outcome of pregnancy (including abortion) and, to a lesser extent, by the influence of maternal anxiety on the diagnosis of doubtful malformations. It is also very unlikely that any drug in common use in 1964 had even a minor influence on congenital malformations recognisable in the first six weeks of life. ER -