RT Journal Article
SR Electronic
T1 Morbidity and drugs in pregnancy
JF The Journal of the Royal College of General Practitioners
JO J R Coll Gen Pract
FD British Journal of General Practice
SP 631
OP 645
VO 25
IS 158
A1 The Birmingham Research Unit of the Royal College of General Practitioners
YR 1975
UL http://bjgp.org/content/25/158/631.abstract
AB In a prospective study involving 9,000 pregnant women, no cause-and-effect relationships have been established between morbidity recorded or drugs taken during early pregnancy and subsequent congenital malformations. The relationships that have been identified are largely explained by the influence of a history of a previous abnormal outcome of pregnancy (including abortion) and, to a lesser extent, by the influence of maternal anxiety on the diagnosis of doubtful malformations. It is also very unlikely that any drug in common use in 1964 had even a minor influence on congenital malformations recognisable in the first six weeks of life.