TY - JOUR T1 - Where to find a disease JF - British Journal of General Practice JO - Br J Gen Pract SP - 540 LP - 540 DO - 10.3399/bjgp22X721145 VL - 72 IS - 724 AU - Tim Senior Y1 - 2022/11/01 UR - http://bjgp.org/content/72/724/540.abstract N2 - Where do diseases live? It seems an odd question, but perhaps an important one, because we need to find a disease in order to treat it. Some simple examples show how obvious this is. If someone fractures their ankle, that’s where the pathology is, and we’d be pretty foolish to apply a cast to their wrist. Similarly, someone with a urinary tract infection has disease located in their urine, and we even literally go looking for it with a microscope and agar plates. In fact, all infections have an external pathogen invading a particular location in the body to cause disease. Sometimes the location of the disease is a bit less clear cut. A fractured vertebra may also … ER -