RT Journal Article
SR Electronic
T1 Once daily sotalol in the treatment of hypertension
JF The Journal of the Royal College of General Practitioners
JO J R Coll Gen Pract
FD British Journal of General Practice
SP 742
OP 745
VO 27
IS 185
A1 H. L. Shaw
YR 1977
UL http://bjgp.org/content/27/185/742.abstract
AB In a small group of hypertensive patients studied at home, once daily early morning sotalol therapy effectively decreased lying, standing, and post-exercise blood pressure and pulse rate. A dose-response relationship was seen. Adverse effects were mild and transient. The once daily regimen is easy to administer and appears to give precision in blood pressure reduction. Providing there is no subsequent escape from control, once daily beta-blocking therapy should aid long-term hypertension treatment in general practice.