RT Journal Article
SR Electronic
T1 Hypnotics and hangovers: a pilot study of chlormezanone in general practice
JF The Journal of the Royal College of General Practitioners
JO J R Coll Gen Pract
FD British Journal of General Practice
SP 753
OP 757
VO 32
IS 245
A1 A. D. Clift
A1 L. E. Burns
YR 1982
UL http://bjgp.org/content/32/245/753.abstract
AB Ten patients were included in this pilot study of chlormezanone, assessing its effects on duration and quantity of sleep and daytime performance using a pursuit rotor and a digit symbol test. Comparisons of the sleep assessments favoured chlormezanone, although the differences were not statistically significant. There was no evidence of any reduction in daytime performance after chlormezanone. The comparison of chlormezanone and placebo on the pursuit rotor test and the visual analogue assessment of hangover both slightly favoured the drug, but there were no significant differences. The study has demonstrated that it is feasible to evaluate hypnotic drugs more exactly in general practice.