RT Journal Article SR Electronic T1 Single-dose and seven-day trimethoprim and co-trimoxazole in the treatment of urinary tract infection JF The Journal of the Royal College of General Practitioners JO J R Coll Gen Pract FD British Journal of General Practice SP 585 OP 589 VO 33 IS 254 A1 R. H. Jones YR 1983 UL http://bjgp.org/content/33/254/585.abstract AB One hundred and sixteen adults with symptoms of acute urinary tract infection were randomly collected into four groups and given single-dose or seven-day treatment with trimethoprim or co-trimoxazole. Of the 105 patients who completed the study, bacterial urinary infection was present in 70 patients (67 per cent). The rates for symptomatic and bacterial cures were high and indistinguishable between the groups, and there was no difference in the rate of recurrence of urinary infection in the six weeks after treatment. Side effects were lower in the group receiving single-dose trimethoprim (P=0.09).