RT Journal Article SR Electronic T1 Is the treatment of scabies hazardous? JF The Journal of the Royal College of General Practitioners JO J R Coll Gen Pract FD British Journal of General Practice SP 468 OP 469 VO 38 IS 315 A1 Clare Wilkinson YR 1988 UL http://bjgp.org/content/38/315/468.abstract AB Treatment for scabies is usually initiated by general practitioners; most consider lindane (gamma benzene hexachloride) the treatment of choice. Lindane is also widely used as an agricultural and industrial pesticide, and as a result the toxic profile of this insecticide is well understood. Evidence is accumulating that lindane can be toxic to the central nervous system and may be associated with aplastic anaemia. Preparations containing lindane continue to be sold over the counter and may represent a hazard to poorly informed patients. This literature review suggests that general practitioners should prescribe scabicides with increased caution for certain at-risk groups, and give adequate warnings regarding potential toxicity.