TY - JOUR T1 - Lyme disease: a review. JF - British Journal of General Practice JO - Br J Gen Pract SP - 72 LP - 74 VL - 40 IS - 331 AU - D Nathwani AU - N Hamlet AU - E Walker Y1 - 1990/02/01 UR - http://bjgp.org/content/40/331/72.abstract N2 - In the last decade, Lyme borreliosis has emerged as a complex new infection whose distribution is worldwide. The multisystem disorder, which primarily affects the skin, joints, heart and nervous system at different stages, is caused by the tick-borne spirochaete Borrelia burgdorferi. After the first weeks of infection almost all patients have a positive antibody response to the spirochaete and serological determinations are currently the most practical laboratory aid in diagnosis. Treatment with appropriate antibiotics is usually curative. ER -