All | Eligible for 12-month follow-up | Eligible for 24-month follow-up | |
---|---|---|---|
Patients enrolled, n | 1906 | 1419 | 825 |
Age in years, mean (SD) | 49.4 (13.5) | 49.9 (13.6) | 50.4 (13.7) |
Females, n (%) | 1468 (77.0) | 1070 (75.4) | 616 (74.7) |
Males, n (%) | 438 (23.0) | 349 (24.6) | 209 (25.3) |
BMI kg/m2, mean (SD) | 37.1 (6.0) | 37.0 (6.1) | 37.1 (5.6) |
BMI ≥40 kg/m2, n (%) | 485 (25.4) | 355 (25.0) | 213 (25.8) |
Diabetes present, n (%) | 258 (13.5) | 202 (14.2) | 127 (15.4) |
Impaired fasting glucosea, n (%) | 119/1205 (9.9) | 97/891 (10.9) | 59/536 (11.0) |
Cardiovascular diseaseb, n (%) | 152 (8.0) | 117 (8.2) | 71 (8.6) |
Hypertension, n (%) | 612 (32.1) | 469 (33.1) | 265 (32.1) |
Hypertension or raised blood pressurec, n (%) | 1153 (60.5) | 873 (61.5) | 512 (62.1) |
Hyperlipidaemia, n (%) | 239 (12.5) | 187 (13.2) | 120 (14.5) |
Hyperlipidaemia or raised total cholesterold, n (%) | 958 (50.3) | 725 (51.1) | 436 (52.8) |
Comorbiditye ≥1, n (%) | 1408 (73.9) | 1069 (75.3) | 628 (76.1) |
Comorbiditye ≥2, n (%) | 916 (48.1) | 711 (50.1) | 413 (50.1) |
Comorbiditye ≥3, n (%) | 533 (28.0) | 415 (29.2) | 240 (29.1) |
Ex-smoker, n (%) | 575/1852 (30.2) | 453/1380 (31.9) | 253/804 (31.5) |
Practice in affluent areaf, n (%) | 651 (34.2) | 477 (33.6) | 267 (32.4) |
Practice in intermediate deprivation areaf, n (%) | 562 (29.5) | 425 (30.0) | 265 (32.1) |
Practice in deprived areaf, n (%) | 693 (36.4) | 517 (36.4) | 293 (35.5) |
↵a International Diabetes Federation definition 6.1–6.9 mmol/L.
↵b Inclusive of myocardial infarction (MI), angina, congestive cardiac failure, transient ischaemic attack (TIA)/stroke.
↵c Hypertension as marked on practice record, or systolic blood pressure (BP) ≥140mmHg or diastolic BP ≥90mmHg (≥130 or ≥80 for diabetes).
↵d Hyperlipidaemia as marked on record or total cholesterol >5.
↵e Diabetes, angina, hypertension, hyperlipidaemia, MI, congestive cardiac failure, TIA/cardiovascular disease/stroke, oedema, arthritis, depression, breathlessness, back pain, hypothyroidism, sleep apnoea, polycystic ovary syndrome.
↵f Affluent = E8–10, S1–2; Intermediate = E4–7, S3–5; Deprived = E1–3, S6–7 (E = England, S = Scotland).22,23 BMI = Body Mass Index.