Table 1

Aspects of inappropriate prescribing including examples for each aspect.

ExampleDescription of the problem
1. Medicine not useful (no indication, no proven effectiveness or better/safer alternatives available)Prescribing clofibrate, for which much safer and more effective alternatives exits
2. Medicine inappropriate for use in older patientsPrescribing diazepam, which has a long half-life time
3. Prolonged prescribing of hypnoticsMedicine is not taken for a correct duration
4. Dosage exceeds the suitable dosage for older patientsPrescribing flurazepam in a dosage exceeding 15 mg daily
5. Unnecessary therapeutic duplication benzodiazepinePrescribing cylcobarbital and a
6. Contraindication known (drug–disease interaction)Prescribing indometacin to a patient suffering from heart failure
7. Medicine used for treatment of a side-effect caused by another medicineOmeprazole for treatment of stomach problems probably caused by ketoprofen (NSAID)
8. Interaction with another medicine (drug–drug interaction)Prescribing cotrimoxazol to a patient using acenocoumarol (coumarin-derivative) that causes problems in managing INR
9. Omission of drug therapy that is indicated for the treatment or prevention of a conditionLack of prescribing a laxative to a patient
10. Medicine used in/provided by unsuitable administration aids for older peoplePrescribing different types of inhalation devices to one patient