Intervention | Control | |||||
---|---|---|---|---|---|---|
Complete withdrawal | Reduce dose >50% or persist | Complete withdrawal | Reduce dose >50% or persist | RR | 95% CI | |
Total | 33 | 38 | 6 | 58 | 4.97 | 2.2 to 11.1 |
Men | 6 | 7 | 2 | 10 | 2.8 | 0.7 to 11.2 |
Women | 27 | 33 | 4 | 50 | 6.1 | 2.3 to 16.2 |
Without depressiona | 20 | 27 | 3 | 36 | 5.5 | 1.8 to 17.2 |
Depressed patientsa | 7 | 9 | 3 | 19 | 3.2 | 0.9 to 10.5 |
Low doseb | 30 | 27 | 5 | 47 | 5.5 | 2.3 to 13.0 |
High doseb | 2 | 13 | 1 | 13 | 1.9 | 0.2 to 18.4 |
Short half-lifec | 28 | 34 | 4 | 46 | 5.6 | 2.1 to 15.0 |
Long half-lifec | 5 | 6 | 2 | 13 | 3.4 | 0.8 to 14.4 |