Distribution of sex and age by off-label prescribing.
| Children with licensed prescribing (%) | Off-label prescription (%) | χ2 test for trenda (P-value) | |
|---|---|---|---|
| Total number of children | 16 113 | 1050 | |
| Males | 9198 (57.1) | 602 (57.3) | 0.016 |
| Females | 6915 (42.9) | 448 (42.7) | (0.900) |
| Age in years | |||
| 0–2 | 452 (2.8) | 89 (8.5) | |
| 3–5 | 2190 (13.6) | 266 (25.3) | 81.885 |
| 6–11 | 7867 (48.5) | 353 (33.5) | (<0.001) |
| 12–16 | 5548 (34.5) | 340 (32.4) | |
Fifty-eight patients (two with ‘off-label’ prescriptions) did not have a valid age recorded.
↵a Degrees of freedom = 1.