Description | Baseline value | Minimum value | Maximum value |
---|---|---|---|
Prevalence constant | 0.25 | 0.2 | 0.4 |
Cost of urea breath test | £20.00 | £15.00 | £21.05 |
Cost of serology | £8.50 | £7.50 | £9.38 |
Cost of faecal antigen test | £14.00 | £12.00 | £19.00 |
Cost of eradication treatment | £30.00 | £9.00 | £38.00 |
Cost of missed diagnosis — based on cost of gastroscopy (£196), cost of 2 months of high dose PPI (£44), and one extra GP visit (£20) | £260 | £0 | £500 |
Sensitivity of urea breath test | 0.97 | 0.80 | 0.99 |
Sensitivity of serology | 0.91 | 0.80 | 0.95 |
Sensitivity of faecal antigen test | 0.96 | 0.80 | 0.97 |
Specificity of urea breath test | 0.96 | 0.80 | 0.99 |
Specificity of serology | 0.90 | 0.70 | 0.90 |
Specificity of faecal antigen test | 0.97 | 0.80 | 0.97 |
PPI = protein pump inhibitor.
↵a For the least effective test, the incremental cost-effectiveness ratio (ICER) is equivalent to the mean cost per true positive. For the remaining tests, the ICER is calculated as the difference in cost divided by the difference in effectiveness.