Table 3

Risk of relevant cancer within 2 years of first consultation for bleeding (all patients).

Rectal bleeding n = 29 007Postmenopausal bleeding n = 10 122
CharacteristicHazard ratioa95% CIHazard ratioa95% CI
Sex
 Female1.00
 Male1.721.46 to 2.01
Age group (years)
 54 or lessb1.001.00
 55–644.543.48 to 5.923.801.92 to 7.52
 65–747.145.52 to 9.228.914.51 to 17.63
 75 and over9.147.05 to 11.8512.986.47 to 26.04
Body mass index (BMI)
 Normal (<25)1.001.00
 Overweight (25–29.9)1.040.85 to 1.281.390.89 to 2.17
 Obese (≥30)1.130.88 to 1.442.001.26 to 3.10
 No valid BMI recorded1.000.77 to 1.311.580.92 to 2.73
Smoking status
 Non–smoker1.001.00
 Smoker0.720.56 to 0.931.130.68 to 1.88
 Not recorded0.860.65 to 1.151.10.64 to 1.90
HRT medication
 Previous user/none recorded1.00
 User in last 12 months0.310.18 to 0.55
  • a Adjusted for all other variables in table plus deprivation, blood pressure, and comorbidities.

  • b Minimum age 25 years for rectal bleeding, 40 years for postmenopausal bleeding. HRT = hormone replacement therapy.