Table 4

Costs and savings caused by the intervention (multilevel statistics); all recommendations are included.

Cost changes per patient, €a
Written feedback (n)Case conferences (n)P-valueDifference (95% CI)
Costs caused by time expenses on the total process of medication review
 GPb6.22 (97)8.68 (163)
 Pharmacist9.69 (350)c15.03 (387)0.0015.27 (2.21 to 8.34)
Savings due to medication changes at 9 months after intervention−4.33 (320)−7.78 (365)0.3573.44 (−3.89 to 10.77)
Yearly savings in medicine costs for each year that medication change persists−7.79 (320)−12.24 (365)0.4434.44 (−6.90 to 12.81)
Net expenses at 9 months after medication review (including pharmacy costs and savings on medicines)5.52 (319)7.23 (365)0.6551.72 (−5.80 to 9.23)
Net expenses at 9 months after medication review (including pharmacy and GP costs and savings on medicines)14.22 (89)13.71 (153)
  • a Positive number = expenses, negative number = savings.

  • b From GPs, time logs for only 37% of all participants were received.

  • c For one patient the time log from the pharmacy got lost, so this patient was excluded from this analysis.