Table 1

Glycaemic control in people with type 2 diabetes prescribed two or more oral agents concurrently.

Number of types of oral agents prescribednPre-therapy HbA1ca Mean % (SD)Post-therapy HbA1cb Mean % (SD)Mean difference % Pre-HbA1c – Post-HbA1c (95% CI)P-valueNumber (%) with HbA1c ≥7.5% post-therapyNumber (%) with HbA1c ≥8.5% post-therapy
≥250649.07 (1.51)8.16 (1.57)0.91 (0.86 to 0.95)<0.0013153 (62.26)1712 (33.81)
241749.04 (1.51)8.04 (1.51)1.00 (0.95 to 1.05)<0.0012468 (59.13)1280 (30.67)
38549.21 (1.49)8.73 (1.72)0.48 (0.37 to 0.59)<0.001658 (77.05)411 (48.13)
4369.16 (1.49)9.34 (2.18)−0.19 (−0.79 to 0.42)0.5427 (75.00)21 (58.33)
Pre-200327139.22 (1.56)8.28 (1.66)0.93 (0.87 to 0.99)<0.0011755 (64.69)1023 (37.71)
Post-200323518.90 (1.43)8.02 (1.46)0.87 (0.81 to 0.94)<0.0011398 (59.46)689 (29.31)
  • a Pre-therapy HbA1c (haemoglobin A1c) is the last available HbA1c assessment in the 6 months prior to initiation of a patient's last oral agent.

  • b Post-therapy HbA1c is the last available HbA1c assessment in the 6 months following initiation of their last oral agent.