Frequency of clinical features in cases and controls.
| Variable | Cases, n (%),n = 3505 | Controls, n (%),n = 24 021 | LR (95% CI) | PPVa(95% CI) |
|---|---|---|---|---|
| Headache | 362 (10.2) | 261 (2.6) | 6.9 (6.2 to 7.1) | 0.09% (0.08 to 0.10) |
| Motor loss | 308 (8.7) | 731 (3.1) | 21.(1.9 to 2.4) | 0.026% (0.024 to 0.030) |
| New-onset seizure | 154 (4.4) | 8 (0.05) | 96 (81 to 110) | 1.2% (1.0 to 1.4) |
| Confusion | 109 (3.1) | 47 (0.2) | 16 (13 to 19) | 0.20% (0.16 to 0.24) |
| Weakness | 95 (2.7) | 42 (0.2) | 11 (9.1 to 14) | 0.14% (0.11 to 0.18) |
| Memory loss | 37 (1.1) | 64 (0.4) | 2.9 (2.0 to 4.1) | 0.036% (0.026 to 0.052) |
| Visual disorder | 35 (1.0) | 62 (0.3) | 2.8 (2.0 to 4.1) | 0.035% (0.025 to 0.051) |
LR = likelihood ratio
↵a Positive predictive value in the consulting population.