Mean ratings and standard deviations for HADS and WHQ subscalesa including the level of significance as found by MANCOVA analysis (age as covariate).
| Section | Pre-menopause n = 42 | Peri-menopause n = 25 | Post-menopause n = 38 | HRT n = 36 | Pill n = 31 | Number of items | Significance (MANCOVA) |
|---|---|---|---|---|---|---|---|
| HADS — anxiety (SD) | 6.48 (3.72) | 8.20 (3.54) | 7.03 (4.51) | 6.97 (3.23) | 8.34 (4.56) | 7 | 0.20 |
| HADS — depression (SD) | 4.21 (3.46) | 4.12 (3.33) | 3.76 (3.00) | 5.14 (3.70) | 5.10 (4.43) | 7 | 0.64 |
| WHQ — somatic (SD) | 0.37 (0.26) | 0.52 (0.27) | 0.51 (0.29) | 0.50 (0.26) | 0.48 (0.27) | 7 | 0.39 |
| WHQ — memory (SD) | 0.33 (0.33) | 0.53 (0.41) | 0.42 (0.40) | 0.47 (0.35) | 0.46 (0.35) | 3 | 0.25 |
| WHQ — sexual (SD) | 0.23 (0.25) | 0.41 (0.35) | 0.40 (0.36) | 0.44 (0.40) | 0.21 (0.27) | 3 | 0.82 |
| WHQ — sleep (SD) | 0.38 (0.34) | 0.52 (0.36) | 0.50 (0.36) | 0.49 (0.37) | 0.48 (0.34) | 3 | 0.67 |
| WHQ — attractiveness (SD) | 0.57 (0.38) | 0.64 (0.40) | 0.54 (0.36) | 0.56 (0.37) | 0.60 (0.37) | 2 | 0.60 |
| WHQ — vasomotor (SD) | 0.17 (0.33) | 0.42 (0.40) | 0.57 (0.46) | 0.42 (0.44) | 0.26 (0.36) | 2 | 0.41 |
| WHQ — menstrual (SD) | 0.46 (0.29) | 0.58 (0.31) | 0.28 (0.25) | 0.39 (0.29) | 0.48 (0.32) | 2 | 0.01b |
| Difficulty coping with any of the WHQ symptoms (%) | 25.6 | 34.8 | 33.3 | 57.1 | 34.6 | 8.57c,d |
↵aAlthough WHQ also measures anxiety and depression, the two subscales were not included as they were already addressed by HADS.
↵bP<0.01.
↵cχ2 test.
↵dNon-significant.
HADS = hospital anxiety and depression scale; WHQ = women's health questionnaire; HRT = hormone replacement therapy; MANCOVA = multivariate analysis of covariance; SD = standard deviation.