Medication use in patients and controlsa (n = 118).
| Patients | Controls | P-value | Odds ratio (95% CI) | |
|---|---|---|---|---|
| Number of somatic medications per year (mean [range]) | 2.6 (0–18.0) | 1.5 (0–7.5) | <0.001b | – |
| Number of psychotropic drugs per year (mean [range]) | 0.4 (0–9.0) | 0.05 (0–0.62) | <0.001 | – |
| Number of patients using psychotropic drugs (n [%]) | ||||
| Antidepressants | 42 (35.6) | 7 (5.9) | – | 7.5 (3.1 to 18.9) |
| Benzodiazepines | 62 (52.5) | 15 (12.7) | – | 5.8 (3.0 to 11.1) |
| Others | 3 (2.5) | 3 (2.5) | – | 1.0 |
| Days of psychotropic drug use per year (median [range]) | ||||
| Antidepressants | 19.5 (1.9–297.0)c | 5.0 (1.62–91.7)d | – | – |
| Benzodiazepines | 8.9 (0.4–322.5)c | 4.2 (1.1–90.8)d | – | – |
| Others | 34.3 (1.7–58.2)c | 3.8 (0.2–25.1)d | – | – |
| Prescribed daily doses (mean [range]) | ||||
| Antidepressants | 0.76 (0.20–1.37)c | 0.77 (0.13–2.00)d | – | – |
| Benzodiazepines | 0.62 (0.06–1.50)c | 0.61 (0.20–1.54)d | – | – |
| Others | 0.51 (0.25–0.75)c | 0.31 (0.25–0.40)d | – | – |
↵an = 118: one general practice did not use the computerised registration, so medication could not be established in this practice.
↵bStatistically significant difference between patients and controls P<0.05.
↵cFor patients with antidepressants, benzodiazepines and other psychotropic drugs, n = 42, 62, and 3, respectively.
↵dFor patients with antidepressants, benzodiazepines and other psychotropic drugs, n = 7, 15, and 3, respectively.