Table 2

Timing of and reasons for withdrawal from OA and ADHD n-of-1 trials.

Number of patients
OA n-of-1 trial
Timing of withdrawal
 In first treatment period10
 In second treatment period4
 In third treatment period0
Reason for withdrawal
 Side effects6 (1 on placebo)
 Tablets not helping4
 Could not cope1
 Ill health1
 Too many tablets1
 Serious adverse event1
ADHD n-of-1 trial
Timing of withdrawal
 In first treatment period1
 In second treatment period2
 In third treatment period1
Reason for withdrawal
 Deterioration on placebo2
 Side effects1
 No teacher input1
  • ADHD = attention deficit hyperactivity disorder. OA = osteoarthritis.