Table 4
Random effects meta-analysis of efficacy of topical antibiotics versus placebo in improving late (6–10 days) microbiological remission.
| Study or sub-category | Treatment n/N | Control n/N | RR (random) 95% CI | Weight % | RR (random) 95% CI |
|---|---|---|---|---|---|
| Gigliotti 1984 | 27/34 | 10/32 |  | 16.88 | 2.54 (1.48 to 4.37) |
| Miller 1992 | 59/76 | 35/67 | 30.67 | 1.49 (1.15 to 1.93) | |
| Rietveld 2005 | 16/21 | 12/29 | 18.68 | 1.84 (1.12 to 3.02) | |
| Rose 2005 | 81/125 | 69/125 | 33.76 | 1.17 (0.96 to 1.44) | |
| Total (95% CI) | 256 | 253 | 100.0 | 1.56 (1.17 to 2.09) | |
| Total events: 183 (treatment), 126 (control) | |||||
| Test for heterogeneity:χ2 = 9.01, degrees of freedom = 3 (P = 0.03), l2 = 66.7% | |||||
| Test for overall effect: Z = 3.01 (P = 0.003) | |||||
n = number of subjects in remission. N = number of subjects tested. RR = relative risk.