Table 2

Random effects meta-analysis of efficacy of topical antibiotics versus placebo in improving late (6–10 days) clinical remission.

Study or sub-categoryTreatment n/NControl n/NRR (random) 95% CIWeight %RR (random) 95% CI
Gigliotti 198431/3423/32Embedded Image13.261.27 (1.00 to 1.61)
Rietveld 200545/7353/9012.281.05 (0.82 to 1.21)
Rose 2005140/163128/16374.461.09 (0.99 to 1.21)
Total (95% CI)270285100.001.11 (1.01 to 1.21)
Total events: 216 (treatment), 204 (control)
Test for heterogeneity:χ2 = 1.49, degrees of freedom = 2 (P = 0.47), l2 = 0%
Test for overall effect: Z = 2.31 (P = 0.02)
  • n = number of subjects in remission. N = number of subjects tested. RR = relative risk.