Table 2

Crude and adjusted associations between blood pressure control and medication usage.

VariableBlood pressure uncontrolled n (%)Blood pressure controlled n (%)Crude odds ratio95% CIAdjusted odds ratioa95% CI
Medication total
 161 (49)64 (51)1
 2106 (46)123 (54)0.900.58 to 1.400.940.57 to 1.55
 ≥394 (52)88 (48)1.120.71 to 1.771.260.78 to 2.03
Drug modifications
 071 (44)92 (56)1
 157 (55)44 (45)1.681.01 to 2.781.681.01 to 2.79
 240 (47)45 (53)1.150.68 to 1.951.170.66 to 2.06
 ≥393 (50)94 (50)1.280.84 to 1.961.330.89 to 1.99
Drug changes
 0180 (47)204 (53)1
 159 (54)50 (46)1.340.87 to 2.051.380.98 to 1.95
 ≥222 (51)21 (49)1.190.63 to 2.231.110.62 to 2.00
Drug intensifications
 077 (44)98 (56)1
 164 (54)53 (46)1.540.96 to 2.471.571.22 to 2.03
 242 (48)45 (52)1.190.71 to 1.991.200.78 to 1.82
 ≥378 (50)79 (50)1.260.81 to 1.941.320.91 to 1.92
Drug diminutions
 0180 (48)194 (52)1
 152 (47)56 (53)1.000.66 to 1.541.060.66 to 1.70
 ≥229 (54)25 (46)1.250.70 to 2.221.260.71 to 2.26
  • Blood pressure control = <150/90 mmHg. CI = confidence interval. Odds ratio >1 = association with worse blood pressure control; <1 = association with improved blood pressure control.

  • Adjusted for age band and number of comorbidities.

    • Drug modifications are classed as the total of drug changes and drug intensifications combined.

    • Drug changes are classed as changing one class of drug for another or stopping a drug and replacing it with another from the same class.

    • Drug intensifications are classed as adding in a new drug or increasing a drug dosage.

    • Drug diminutions are classed as stopping a drug and not replacing it or decreasing a drug dosage.