Percentage weight change
≥5% loss0 to <5% lossGain
Participants, nb275026
Weight change, %, mean (SD)−7.45 (1.88)−2.53 (1.53)2.54 (1.90)
Systolic blood pressure, mmHg
 Baseline, mean (SD)136.6 (15.86)131.1 (18.97)135.5 (24.84)
 Final, mean (SD)126.2 (13.87)126.6 (15.51)133.2 (19.11)
 Difference (95% CI)−10.0 (−15.5 to −4.5)−4.5 (−8.8 to −0.24)−2.4 (−11.4 to 6.6)
Diastolic blood pressure (mmHg)
 Baseline, mean (SD)83.4 (9.10)77.4 (10.41)83.5 (10.04)
 Final, mean (SD)77.3 (7.33)76.0 (9.86)81.8 (8.62)
 Difference (95% CI)−6.2 (−8.9 to −3.4)−1.4 (−4.0 to 1.2)−1.6 (−6.2 to 2.9)
Fasting glucose, mmol/L
 Baseline, mean (SD)5.17 (0.51)5.41 (1.14)5.24 (0.75)
 Final, mean (SD)5.09 (0.57)5.21 (1.08)5.41 (0.90)
 Difference (95% CI)−0.08 (−0.28 to 0.11)−0.20 (−0.42 to 0.03)0.17 (−0.21 to 0.56)
Total cholesterol, mmol/L
 Baseline, mean (SD)5.21 (1.26)4.91 (1.15)4.84 (1.12)
 Final, mean (SD)4.99 (1.11)5.10 (1.09)4.80 (1.26)
 Difference (95% CI)−0.23 (−0.61 to 0.15)0.19 (−0.08 to 0.47)−0.04 (−0.42 to 0.35)
HDL cholesterol, mmol/L
 Baseline, mean (SD)1.31 (0.40)1.40 (0.34)1.30 (0.41)
 Final, mean (SD)1.36 (0.33)1.41 (0.39)1.33 (0.44)
 Difference (95% CI)0.05 (−0.07 to 0.17)0.01 (−0.05 to 0.07)0.04 (−0.09 to 0.16)
LDL cholesterol, mmol/L
 Baseline, mean (SD)2.89 (0.97)2.99 (0.93)2.81 (0.85)
 Final, mean (SD)2.86 (1.05)3.10 (0.98)3.01 (1.17)
 Difference (95% CI)−0.04 (−0.49 to 0.41)0.11 (−0.11 to 0.33)0.21 (−0.18 to 0.60)
Total/HDL cholesterol ratio
 Baseline, mean (SD)4.08 (1.23)3.84 (0.99)4.13 (1.60)
 Final, mean (SD)3.86 (1.17)3.89 (1.02)3.99 (1.27)
 Difference (95% CI)−0.22 (−0.59 to 0.16)0.06 (−0.15 to 0.26)−0.14 (−0.64 to 0.36)
Fasting triglyceride, mmol/L
 Baseline, mean (SD)1.69 (0.65)1.52 (0.95)1.74 (1.21)
 Final, mean (SD)1.42 (0.71)1.65 (1.73)1.61 (0.81)
 Difference (95% CI)−0.26 (−0.57 to 0.04)0.13 (−0.33 to 0.58)−0.12 (−0.40 to 0.16)
  • a Negative differences represent a favourable outcome.

  • b Number of participants varies for different variables due to missing data. HDL = high-density lipoprotein. LDL = low-density lipoprotein.