Study | Water-based | Oil-based | Odds ratio (95% CI) |
---|---|---|---|
Dubow30 | 21/40 | 8/19 | 1.5 (0.4 to 5.3) |
GP Research Group33 | 39/47 | 48/60 | 1.2 (0.4 to 3.8) |
Fraser14 | 147/174 | 66/74 | 0.7 (0.2 to 1.6) |
Chaput de Saintonge and Johnstone34 | 21/35 | 20/32 | 0.9 (0.3 to 2.7) |
Eekhof et al42 | 21/22 | 19/20 | 1.1 (0.01 to 90.8) |
Total | 249/318 | 161/205 | 1.0 (0.6 to 1.6) |
Heterogeneity | Woolf Q = 1.7, df = 4, P = 0.8 | ||
Overall effect | χ2 = 0.02, df = 1, P = 0.9 | ||
Docusate (water-based) | TEPb (water-based) | ||
Fraser14 | 23/26 | 19/24 | 2.0 (0.3 to 14.5) |
Singer et al41 | 17/23 | 6/21 | 7.1 (1.6 to 33.1) |
Meehan et al44 | 5/15 | 8/17 | 0.6 (0.1 to 2.9) |
Whatley et al45 | 18/34 | 13/30 | (0.1 to 2.9) |
Total | 63/98 | 46/92 | 1.9 (0.7 to 5.0) |
Heterogeneity | Woolf Q = 6.8, df = 3, P = 0.08 | ||
Overall effect | χ2 = 1.53, df = 1, P = 0.2 | ||
Docusate (water-based) | Saline (water-based) | ||
Meehan et al44 | 5/15 | 8/16 | 0.5 (0.09 to 2.6) |
Whatley et al45 | 18/34 | 19/28 | 0.5 (0.2 to 1.7) |
Total | 23/49 | 27/44 | 0.5 (0.2 to 1.2) |
Heterogeneity | Woolf Q = 0.004, df = 1, P = 0.9 | ||
Overall effect | χ2 = 2.3, df = 1, P = 0.1 | ||
TEP (water-based) | Saline (water-based) | ||
Meehan et al44 | 8/17 | 8/16 | 0.9 (0.2 to 4.3) |
Whatley et al45 | 13/30 | 19/28 | 0.4 (0.1 to 1.2) |
Total | 21/47 | 27/44 | 0.5 (0.2 to 1.2) |
Heterogeneity | Woolf Q = 1.0, df = 1, P = 0.3 | ||
Overall effect | χ2 = 2.35, df = 1, P = 0.1 | ||
Dioctyl (oil-based) | Oil (oil-based) | ||
GP Research Group31 | 54/77 | 42/73 | 1.7 (0.8 to 3.6) |
Burgess32 | 19/34 | 33/41 | 0.3 (0.1 to 1.0) |
Fraser14 | 20/25 | 23/25 | 0.3 (0.03 to 2.5) |
Total | 93/136 | 98/139 | 0.6 (0.2 to 2.4) |
Heterogeneity | Woolf Q=9.0, df=2, P=0.01 | ||
Overall effect | χ2=0.5, df=1, P=0.5 |
df = degrees of freedom. TEP = triethanolamine polypeptide. An extended version of this table can be found online (Supplementary Table 5).