Table 5

Timing of pneumococcal vaccination for all pneumonia cases and for cases with lobar or pneumococcal pneumonia and their matched controls.

Cases, n (%)Controls, n (%)Adjusteda OR (95% CI)
Timing of pneumococcal vaccination before pneumonia diagnosis
Patients with ≥5 years of medical records (17 172 cases and 71 399 controls)
 No recorded use in last 5 years14351 (83.6)61136 (85.6)1.00
 ≥49 months ago476 (2.8)1525 (2.1)1.11 (0.98 to 1.25)
 12–48 months ago1604 (9.3)5457 (7.6)1.02 (0.95 to 1.10)
 15–365 days ago715 (4.2)3137 (4.4)0.83 (0.76 to 0.92)
 1–14 days ago26 (0.2)144 (0.2)0.67 (0.43 to 1.04)
Patients with ≥10 years of medical records (6642 cases and 27 294 controls)
 No recorded use in last 10 years5429 (81.7)23380 (85.7)1.00
 ≥61 months ago491 (7.4)1287 (4.7)1.18 (1.02 to 1.37)
 49–60 months ago106 (1.6)346 (1.3)0.93 (0.72 to 1.19)
 12–48 months ago402 (6.1)1266 (4.6)1.06 (0.91 to 1.23)
 15–365 days ago202 (3.0)972 (3.6)0.71 (0.59 to 0.86)
 1–14 days ago12 (0.2)43 (0.2)0.95 (0.48 to 1.87)
Timing of pneumococcal vaccination before diagnosis of lobar or pneumococcal pneumonia
Patients with ≥5 years of medical records (4485 cases and 18 596 controls)
 No recorded use in last 5 years3792 (84.6)16135 (86.8)1.00
 ≥49 months ago124 (2.8)351 (1.9)1.23 (0.97 to 1.56)
 12–48 months ago387 (8.6)1279 (6.9)1.05 (0.91 to 1.21)
 15–365 days ago173 (3.9)794 (4.3)0.82 (0.67 to 1.00)
 1–14 days ago9 (0.2)37 (0.2)0.98 (0.45 to 2.14)
Patients with ≥12 months of medical records (7502 cases and 34 941 controls)
 No recorded use in last 12 months7199 (96.0)33615 (96.2)1.00
 15–365 days ago290 (3.87)1260 (3.61)0.88 (0.76 to 1.02)
 1–14 days ago13 (0.17)66 (0.19)0.76 (0.41 to 1.43)
  • a ORs (odds ratios) are adjusted for one or more current risk factors, one or more new potential risk factors, smoking status, Townsend score in quintiles, use of influenza vaccine in last 12 months, number of years of medical records data (5, 6, 7, 8, 9, 10).