Characteristics of responders and non-responders to the feedback questionnaire
| Characteristics | Responders (n = 252), n (%) | Non-responders (n = 349), n (%) | P-valuea |
|---|---|---|---|
| Age group, years | <0.001 | ||
| 18–34 | 69 (27) | 176 (50) | |
| 35–54 | 140 (56) | 143 (41) | |
| 55–74 | 43 (17) | 30 (9) | |
| Sex | 0.001 | ||
| Female | 192 (76) | 216 (62) | |
| Male | 60 (24) | 133 (38) | |
| Ethnicity | 0.046 | ||
| White | 246 (98) | 329 (94) | |
| Otherb | 6 (2) | 20 (6) | |
| Trial centre | 0.039c | ||
| Bristol | 229 (91) | 292 (84) | |
| Birmingham | 21 (8) | 51 (15) | |
| Newcastle | 2 (1) | 6 (2) | |
| Employment status | 0.009 | ||
| Employed | 151 (60) | 206 (59) | |
| Student | 10 (4) | 13 (4) | |
| Retired | 16 (6) | 5 (1) | |
| Houseperson | 31 (12) | 46 (13) | |
| Unemployed job seeker | 10 (4) | 31 (9) | |
| Unemployed due to ill-health | 34 (13) | 48 (14) | |
| History of depression | |||
| Family history | 167 (66) | 210 (60) | 0.14 |
| Previous depression | 183 (73) | 252 (72) | 0.96 |
| Previous antidepressants | 143 (57) | 182 (52) | 0.28 |
| Severity of depressiond | 0.46 | ||
| Mild | 24 (10) | 27 (8) | |
| Moderate | 132 (52) | 173 (50) | |
| Severe | 196 (38) | 149 (43) | |
| Antidepressant treatmente | <0.001 | ||
| Continued on medication | 173 (69) | 165 (47) | |
| Discontinued medication | 79 (31) | 184 (53) | |
↵a In addition to those presented here, a further five variables demonstrated no differences between responders and non-responders and are omitted for brevity, namely drug allocation, side-effects 2 weeks after randomisation, improvement in BDI (halving of baseline score) at 6 and 12 weeks, and remission at 6 weeks (BDI <10).
↵b Other ethnicities: Asian/British Asian (n = 3), Black/Black British (n = 3), mixed (n = 1), other (n = 1).
↵c Fisher's exact test.
↵d ICD-10 depression severity, assessed using the CIS-R.
↵e Self-reported adherence to study medication at last completed follow-up.