 Proportions recommending ‘neostatin’, % (95% CI)  % (95% CI) χ^{2} statistics 

Level 1, NNT = 34, survival gain = 9 months  39.5 (28.7 to 50.3)  25.6 (15.8 to 35.4)  32.7 (25.4 to 40.0)  13.9 (0.5 to 28.3) χ^{2} = 3.5, P = 0.062 

Level 2, NNT = 17, survival gain = 17 months  49.3 (37.9 to 60.8)  31.3 (21.0 to 41.5)  40.0 (32.2 to 47.8)  18.1 (2.9 to 33.3) χ^{2} = 5.3, P = 0.022 

Level 3, NNT = 9, survival gain = 32 months  52.4 (41.5 to 63.3)  43.2 (32.3 to 54.1)  47.9(40.1 to 55.6)  9.2 (6.0 to 24.5) χ^{2}= 1.4, P= 0.238 

Trend analysis^{a} 
Odds ratio per level (95% CI)  1.3 (1.0 to 1.8)  1.5 (1.1 to 2.1)   
Odds ratio for interaction term format × level (95% CI)  1.2 (0.7 to 1.8)   

 Evaluation of ‘neostatin’ on a 010 scale,^{b} score (95% CI)  Mean (95% CI), rank sum statistics 

Level 1, NNT = 34, survival gain = 9 months  5.2 (4.6 to 5.8)  4.7 (4.1 to 5.3)  5.0 (4.6 to 5.4)  0.5 (0.3 to 1.4) z = 1.3, P= 0.189^{c} 

Level 2, NNT = 17, survival gain = 17 months  6.2 (5.7 to 6.8)  5.0 (4.4 to 5.6)  5.6 (5.2 to 6.0)  1.2 (0.4 to 2.0) z =3.1, P= 0.002^{c} 

Level 3, NNT = 9, survival gain = 32 months  6.1 (5.6 to 6.6)  5.5 (4.9 to 6.2)  5.8 (5.4 to 6.2)  0.6 (0.3 to 1.4) z = 1.1, P= 0.264^{c} 

Trend analysis^{d} 
Regression coefficient per level  0.42 (0.03 to 0.81)  0.41 (0.03 to 0.85)   
Regression coefficient for interaction term format x level (95% CI)  0.01 (0.59 to 0.58)   