Table 1

Signs and symptoms of possible food allergya,1

IgE mediated (usually evident within minutes)Non-IgE mediated (may be several hours before they present)
 Acute urticaria: localised or generalisedAtopic eczema
 Acute angioedema: most commonly lips, face, around eyes
Gastrointestinal system
 Angioedema: lips, tongue, palateGastroesophageal reflux disease
 Oral pruritusLoose or frequent stools
 NauseaBlood and/or mucus in stools
 Colicky abdominal painAbdominal pain
 VomitingInfantile colic
 DiarrhoeaFood refusal or aversion
Perianal redness
Pallor and tiredness
Faltering growth: in conjunction with at least ≥1 of the above gastrointestinal symptoms (with or without significant atopic eczema)
Respiratory system (usually in combination with ≥1 of the above symptoms and signs)
 Upper respiratory tract symptoms: nasal itching, sneezing, rhinorrhoea, or congestion (with or without conjunctivitis)
 Lower respiratory tract symptoms: cough, chest tightness, wheezing, or shortness of breath
 Signs or symptoms of anaphylaxis or other systemic allergic reactions
  • a This list is not exhaustive. The absence of these symptoms does not exclude food allergy.