Characteristics of principal trials
| Everitt et al, 20066 | Rietveld et al, 20054 | Rose et al, 20055 | |
|---|---|---|---|
| Setting | UK Primary care | The Netherlands Primary care | UK Primary care |
| Participants | 307 adults and children | 181 adults | 326 children aged 6 months to 12 years |
| Study design | Open, factorial, randomised control trial | Double-blind, randomised placebo-controlled trial | Double-blind, randomised placebo-controlled trial |
| Intervention | Immediate chloramphenicol eye drops versus delayed chloramphenicol eye drops versus no eye drops | Fusidic acid gel versus placebo | Chloramphenicol 0.5% versus placebo |
| Determination of cure at day 7 | Patient assessed cure as recorded in a daily diary | GP assessed at day 7 | Parent assessed cure as recorded in a daily diary |