Abstinence at 8 days (n = 170) | Abstinence at 1 month (n = 122) | Abstinence at 3 months (n = 70) | ||||
---|---|---|---|---|---|---|
Variable | Odds ratio (95% CI) | P-value | Odds ratio (95% CI) | P-value | Odds ratio (95% CI) | P-value |
Buprenorphine versus methadone | 1.74 (0.84 to 3.61) | 0.136 | 0.42 (0.17 to 1.05) | 0.065 | 2.14 (0.74 to 6.18) | 0.159 |
In prison versus not in prison at timepoint | 119.48 (27.28 to 523.38) | <0.001 | 186.88 (45.59 to 765.94) | <0.001 | 87.99 (24.63 to 314.29) | <0.001 |
Abstinence at 8 days | N/A | N/A | 4.67 (1.77 to 12.34) | 0.002 | 0.67 (0.20 to 2.22) | 0.515 |
Abstinence at 1 month | N/A | N/A | N/A | N/A | 4.42 (1.44 to 13.55) | 0.009 |
Previous success versus no previous success | 0.92 (0.43 to 1.98) | 0.837 | 0.42 (0.15 to 1.15) | 0.090 | 1.36 (0.46 to 3.96) | 0.578 |
Ethnicity versus white British | ||||||
Asian | 2.72 (0.31 to 23.89) | 0.652 | 0.16 (0.02 to 1.41) | 0.186 | 3.41 (0.27 to 42.50) | 0.822 |
Black | Insufficient data | 0.18 (0.02 to 1.31) | 1.15 (0.07 to 18.44) | |||
Mixed race | Insufficient data | Insufficient data | Insufficient data | |||
White other | 0.81 (0.07 to 9.29) | 0.50 (0.04 to 6.31) | 1.12 (0.05 to 23.70) | |||
Type of use versus injected | ||||||
Smoked | 0.73 (0.34 to 1.55) | 0.647 | 0.97 (0.36 to 2.61) | 0.994 | 0.47 (0.15 to 1.54) | 0.181 |
Injected and smoked | 1.37 (0.16 to 11.69) | 0.89 (0.08 to 9.28) | 0.17 (0.02 to 1.43) | |||
Longest abstinence, per month increase | 0.262 1.00 (0.98 to 1.03) | 0.836 | 1.01 (0.98 to 1.05) | 0.519 | 0.99 (0.96 to 1.02) | 0.406 |
Age (per 1 year increase) | 0.98 (0.92 to 1.04) | 0.460 | 1.10 (1.01 to 1.20) | 0.034 | 1.06 (0.96 to 1.16) | 0.262 |
Years using (per year increase) | 1.05 (0.96 to 1.14) | 0.302 | 0.92 (0.82 to 1.04) | 0.170 | 1.09 (0.96 to 1.24) | 1.198 |
Amount using (per £ increase) | 1.00 (0.99 to 1.01) | 0.819 | 1.00 (0.99 to 1.02) | 0.565 | 1.00 (0.98 to 1.02) | 0.924 |
N/A = not available. ITT = intention-to-treat.