Mean changes in risk parameters between baseline and 12 months in each study group separately and between study groups
| Mean (95% CI) differences between baseline and 12 months | Mean (95% CI) differences over 12 months between study groups (95% CI) | ||
|---|---|---|---|
| Parameter measured | Intensive group | Opportunistic group | |
| % Absolute cardiovascular risk | -0.26 (-0.5 to -0.02)a | -0.03 (-0.28 to 0.22) | -0.23 (-0.58 to 0.12) |
| Systolic blood pressure, mmHg | -4.35 (-5.73 to -2.97)c | -3.96 (-5.38 to -2.53)c | -0.39 (-2.38 to 1.60) |
| Diastolic blood pressure, mmHg | -1.90 (-2.73 to -1.07)c | -1.20 (-2.04 to -0.36)b | -0.70 (-1.88 to 0.48) |
| HDL-cholesterol, mmol/l | 0.01(-0.04 to 0.06) | -0.004 (-0.04 to 0.03) | 0.01 (-0.05 to 0.08) |
| LDL-cholesterol, mmol/l | -0.12 (-0.19 to -0.04)b | 0.01 (-0.05 to 0.08) | -0.13 (-0.23 to -0.03)a |
| Total cholesterol, mmol/l | -0.18 (-0.26 to -0.10)c | -0.05 (-0.12 to 0.03) | -0.14 (-0.25 to -0.03)a |
| Total:HDL-cholesterol ratio | -0.05 (-0.12 to 0.02) | 0.05 (-0.01 to 0.12) | -0.11 (-0.20 to -0.01)a |
| Triglyceride, mmol/l | -0.07 (-0.13 to 0.01)a | 0.02 (-0.05 to 0.09) | -0.09 (-0.18 to 0.004) |
| Waist circumference, cm | -1.49 (-1.97 to -1.01)c | -0.26 (-0.66 to 0.14) | -1.24 (-1.86 to -0.61)c |
| Waist circumference, cm – male | -1.47 (-2.08 to -0.85)c | -0.15 (-0.78 to 0.47) | -1.31 (-2.19 to -0.44)b |
| Waist circumference, cm – female | -1.51 (-2.21 to -0.81)c | -0.31 (-0.83 to 0.21) | -1.20 (-2.07 to -0.32)b |
| Weight, kg | -0.5 (-0.85 to -0.18)b | -0.39 (-0.71 to -0.07)a | -0.12 (-0.58 to 0.34) |
| Body mass index, kg/m2 | -0.18 (-0.30 to -0.06)b | -0.15 (-0.26 to -0.03)a | -0.03 (-0.20 to 0.13) |
| Fasting blood glucose, mmol/l | -0.01 (-0.09 to 0.06) | -0.0004 (-0.10 to 0.10) | -0.01 (-0.14 to 0.12) |
| General Health Questionnaire-28 global score | -1.74 (-2.49 to -0.98)c | -0.65 (-1.40 to 0.11) | -1.09 (-2.16 to -0.02) |