Adjusted hazard ratios (95% CI) for the final model for renal tract cancer for males and females in the derivation cohorta
| Characteristic | Adjusted hazard ratios for females (95% CI) | Adjusted hazard ratios for males (95% CI) |
|---|---|---|
| Smoking status | ||
| Non-smoker | 1.00 | 1.00 |
| Ex-smoker | 1.23 (1.01 to 1.49) | 1.47 (1.32 to 1.63) |
| Light smoker | 1.83 (1.31 to 2.57) | 2.24 (1.84 to 2.73) |
| Moderate smoker | 2.41 (1.87 to 3.12) | 2.49 (2.05 to 3.04) |
| Heavy smoker | 2.32 (1.55 to 3.46) | 2.50 (1.95 to 3.20) |
| Medical history | ||
| History of prior cancer other than renal tract cancer | 1.47 (1.13 to 1.91) | NS |
| Current symptoms and symptoms in preceding year | ||
| Current haematuriab | 119 (85.3 to 167)c | 148 (123 to 177)c |
| Current appetite lossb | 2.45 (1.34 to 4.46) | NS |
| Current abdominal painb | 2.38 (1.97 to 2.89) | 3.06 (2.35 to 3.98)c |
| Current weight lossb | 2.56 (1.75 to 3.74) | 5.67 (3.20 to 10.0)c |
| Anaemia (<11 g/dl) | 1.98 (1.51 to 2.61) | 1.57 (1.27 to 1.94) |
The models also included fractional polynomial terms for age, which were age−2 and age3 for females and age−0.5 for males. The model for females also included an interaction between haematuria and the age terms. The model for males also included interactions between haematuria and age, abdominal pain and age, and weight loss and age.
↵a Hazard ratios adjusted for all other terms in the table and for age.
↵b Compared with person without this characteristic.
↵c Interaction term, hazard ratio evaluated at mean age in females and males.
NS = not significant.