Baseline characteristics
| Total cohort n = 1741 | Aware of diagnosis n = 1026 | Not aware of diagnosis n = 715 | P-valuea | |
|---|---|---|---|---|
| Age, years | 72.9 ± 9 | 71.8 ± 9 | 74.4 ± 8 | <0.001 |
| Sex, female | 1052 (60) | 598 (58) | 454 (64) | 0.032 |
| Ethnicity, white | 1698 (98) | 1001 (98) | 697 (98) | 1.00 |
| eGFR, ml/min/1.73m2 | 52.5 ± 10.4 | 51.5 ± 10.7 | 53.9 ± 9.7 | <0.001 |
| Haemoglobin, g/dl | 13.2 ± 1.4 | 13.2 ± 1.4 | 13.2 ± 1.3 | 0.86 |
| Diabetes mellitus | 294 (17) | 180 (18) | 114 (16) | 0.398 |
| Previous CVE | 387 (22) | 223 (22) | 164(23) | 0.558 |
| On NSAID therapy | 146 (8.4) | 83 (8.1) | 63 (8.8) | 0.60 |
| Ii use | 1123 (65) | 681 (66) | 442 (62) | 0.053 |
| Hypertension | 1528 (88) | 904 (88) | 624 (87) | 0.604 |
| BP <140/90 mmHg | 1117 (64) | 674 (66) | 443 (62) | 0.115 |
| Qualificationb | 788 (45) | 501 (64) | 287 (36) | <0.001 |
| Albuminuriac | 293 (17) | 205 (20) | 88 (12) | <0.001 |
| CKD stage 3Bd | 407 (23) | 285 (28) | 125 (18) | <0.001 |
| Age <75years | 917 (53) | 586 (57) | 331 (46) | <0.001 |
Data are mean ± SD, or number (%). BP = blood pressure. CVE = cardiovascular event. eGFR = estimated glomerular filtration rate. NSAID = non-steroidal anti-inflammatory drug. RAASI = renin–angiotensin–aldosterone system inhibitor.
↵a Patients aware of CKD diagnosis versus those not aware.
↵b Formal educational qualification.
↵c Albuminuria = microalbuminuria or greater amounts of proteinuria.
↵d CKD 3B = eGFR 30–44 ml/min/1.73m2.