Baseline characteristics and results of univariate logistic regression analyses with orthostatic hypotension and orthostatic complaints as dependent variables, (n = 563)
| OR (95% CI) | |||
|---|---|---|---|
| Characteristic | na | OH | Orthostatic complaints |
| Demographics | |||
| Median age, years (IQR) | 75 (72–79) | 0.99 (0.95 to 1.03) | 0.99 (0.95 to 1.05) |
| Male sex (%) | 265/563 (47.1) | 1.06 (0.72 to 1.56) | 0.56 (0.35 to 0.91) |
| Mean body mass index, kg/m2 (SD) | 28.0 (4.2) | 0.97 (0.93 to 1.02) | 1.00 (0.95 to 1.06) |
| Type 2 diabetes mellitus (%) | 352/563 (62.5) | 1.87 (1.22 to 2.85) | 2.16 (1.27 to 3.69) |
| Median duration of diabetes, years (IQR) | 6 (4–10) | 1.00 (0.96 to 1.05) | 1.00 (0.96 to 1.05) |
| Hypertension (%) | 438/563 (77.8) | 1.37 (0.84 to 2.24) | 2.11 (1.08 to 4.11) |
| Macrovascular complications (%) | 175/563 (31.1) | 1.71 (1.15 to 2.56) | 2.13 (1.33 to 3.41) |
| Family history of CVD (%) | 141/563 (25.0) | 1.09 (0.70 to 1.69) | 1.05 (0.62 to 1.79) |
| Measurements | |||
| Consumption meal or drink (%) | 394/558 (70.6) | 0.40 (0.27 to 0.60) | 0.82 (0.50 to 1.35) |
| Mean systolic BP lying, mmHg (SD) | 142.1 (20.5) | 1.31 (1.19 to 1.44) | 0.89 (0.79 to 1.00) |
| Mean diastolic BP lying, mmHg (SD) | 76.1 (9.9) | 1.33 (1.09 to 1.62) | 0.85 (0.67 to 1.08) |
| Mean pulse frequency (SD) | 67.0 (10.8) | 0.99 (0.97 to 1.01) | 1.00 (0.98 to 1.02) |
| Score risk profile (IQR) | 3 (1–6) | 1.02 (0.97 to 1.08) | 1.26 (1.19 to 1.33) |
| Orthostatic complaints (%) | 85/563 (15.1) | 2.02 (1.23 to 3.29) | NA |
| Medication | |||
| Median number of pharmacological agents (IQR) | 5 (3–6) | 1.12 (1.04 to 1.20) | 1.17 (1.08 to 1.27) |
| Median number of antihypertensive agents (IQR) | 2 (0–3) | 1.14 (0.99 to 1.32) | 1.19 (1.01 to 1.41) |
| Antihypertensive medication | 418/563 (74.2) | 1.39 (0.88 to 2.21) | 1.74 (0.96 to 3.15) |
↵a n unless otherwise stated. A high risk of falling was defined as a score of ≥10 points on the risk profile and can be interpreted as a 50% chance of falling twice or more often in the upcoming 3 years. The ORs for systolic and diastolic blood pressure refer to a pressure increase of 10 mmHg. BP = blood pressure. CVD = cardiovascular disease.
IQR = interquartile range. NA = not applicable. OH = orthostatic hypotension. OR = odds ratio. SD = standard deviation.