Adjusted hazard ratio (95% CI) for pancreatic cancera | Adjusted hazard ratio (95% CI) for gastro-oesophageal cancerb | |
---|---|---|
Female | ||
Heartburnc | 2.55 (1.34 to 4.85) | 2.16 (1.29 to 3.64) |
Indigestion without heartburnc | 3.76 (2.83 to 5.01) | 4.30 (3.51 to 5.25) |
Male | ||
Heartburnc | 2.24 (1.11 to 4.55) | 2.95 (2.11 to 4.13) |
Indigestion without heartburnc | 4.64 (3.62 to 5.94) | 6.44 (5.64 to 7.36) |
↵a The models for pancreatic cancer also included fractional polynomial terms for age which were age−2 and age3 for females and age−1 for males; smoking status (five levels), type 2 diabetes, chronic pancreatitis, appetite loss, weight loss, abdominal pain, abdominal distension (females), dysphagia (males), constipation (males). The model for males also included interactions between weight loss and the age terms.
↵b The models for gastro-oesophageal cancer included fractional polynomial terms for age. For females the term was age0.5. For males the terms were age−2, age3. The models for males and females also included smoking status (five levels), dysphagia, abdominal pain, appetite loss, haematemesis, weight loss, anaemia. The model for females also included interactions between the age term and dysphagia, abdominal pain, appetite loss, haematemesis. The model for males included interactions between the age terms and dysphagia.
↵c Compared with person without heartburn or indigestion.