Table 1

Details of included studies

Author, country and health issueStudy design and settingPopulation and participantsNLP Intervention detailsAssessed outcomes and measuresResults
Randomised Controlled Trials
Krugman et al 19
US Speech anxiety
Design: RCT
Setting: University
Assessmen: Baseline and immediately post-treatment
Groups: arm 1) NLP single session; arm 2) self-controlled desensitisation; arm 3) waiting list control
Participants: university undergraduate students
Recruitment: response to advertisement for a programme to alleviate anxiety in public speaking situations. Study baseline, n = 55, 28 male/27 female.
Numbers randomised, analysed and completed not reported Single session
NLP interventionist training: three graduate clinical/counselling psychologists with additional 4 months of NLP training.
Training fidelity checks employed NLP intervention: phobia intervention from ‘Frogs into Princes’:2 Kinaesthetic Anchoring techniques, visualisation
Public speech anxiety.
Personal Report of Confidence as a Speaker Scale. Paul’s Modified Behaviour Checklist. Observed global rating of speech anxiety
Between group differences; no statistical difference between groups (results data not reported). Within group differences (pre-post tests): t values (pre-post tests): t values attained statistical significance (P<0.05) showing reduction in all measures of speech anxiety (including fear expectancy and fear survey) in all three arms.
de Miranda et al 20
Brazil Maternal emotional disturbance and child emotional development
Design: RCT. Setting: day care centre. Assessment: baseline and 9 months post-intervention. Groups: arm 1) NLP; arm 2) control, no further descriptionParticipants: mother and infant pairs. Mothers’ age unreported, child age 18–36 months, sex unreported. Recruitment: not described. Randomised n = 45 (23 NLP/22 control). Completed n = 37. Analysed: children n = 27, mothers n = 37 (10 NLP/27 control)NLP interventionist training: not described. NLP intervention: arm 1) not described beyond ‘NLP’, 15 sessions over 1 yearChild development (Bayley scale). Home environment variation (Home Observation for Measurement of the Environment [HOME] questionnaire). Maternal Mental Health (Self Report Questionnaire)Between Groups: Non-significant trend towards improvement in the HOME environment (P = 0.09). Variations in child mental development (OR 1.21, 95% CI = 0.0 to 23.08, P = 0.669). Maternal mental health: P = 0.26.
Stipancic et al21 Croatia Psychological difficultiesDesign: RCT waiting list controlled trial alternately allocated. Setting: private psychotherapy practice. Assessments: arm 1) baseline, post-treatment and 5 months post-treatment. Arm 2) baseline, 3 months. Groups: arm 1) NLP psychotherapy, arm 2) Wait list controlParticipants: self-referred for psychological difficulties to ‘reduced rate’ psychotherapy: 79% female <21 years = 9%; 21–40 years = 59% >40 years = 31%. Married 24%; employed 56%; college educated or higher 100%. Recruitment: multiple methods. Alternately allocated n = 106 (54 int/52 wait list) Number completed not reported. Analysed n = 54 in int group. Control group analyses not reported.NLP interventionist training: Seven psychotherapists trained to NLP master practitioner level. NLP intervention: individual neurolinguistic psychotherapy (NLPt). Weekly x 60 min sessions. Mean n = 20 (range 5–65).Baseline/screening structured clinical interviews for DSM-IV Personality Disorders. Croatian scale of Quality of LifeBetween groups: ANOVA test found NLP arm resulted in QOL improvement and decreased clinical symptoms (F = 8.114, P = 0.000). Within group findings at 5 months found improvement in intervention compared to baseline (F=3.672, P = 0.019. A small significant interaction was found between number of sessions and size of improvement.
Sorensen et al 22 Denmark Weight maintenanceDesign: RCT. Setting: weight loss clinic. Assessment: baseline pre randomisation, post intervention and at 2 and 3 years. Groups: arm 1) NLP therapy, arm 2) a course in gourmet cookeryParticipants: overweright or obese adults aged 25–55 years. Recruitment: At weight loss clinic following >8% weight loss during 12-week programme. Number in study: randomised n = 48 (23 to NLP, 25 cookery); completed n = 41 (17 NLP, 24 cookery); analysed at 3 years n = 34 (16 NLP, 18 cookery)NLP interventionist training: experienced NLP practitioner (certified by Danish NLP institute). NLP intervention: NLP course arm 1) 10 sessions over 5 months, arm 2) 10 sessions over 5 monthsFasting weight in light clothes to nearest 0.1kg on digital scalesBetween groups: during the 5 months of treatment, there was no significant difference observed between groups for additional weight lost: NLP: –1.8kg versus cookery course: –0.2kg (ANCOVA, NS). After 3 years 57% in the NLP group and 50% in the cookery group had maintained a part of their initial weight loss. There was no significant difference observed between groups (ANCOVA)
Simpson and Dryden23 UK Panic DisorderDesign: equivalence randomised trial. Setting not reported. Assessments: screening, baseline post randomisation, immediately at intervention completion and 4 weeks post completion. Groups: Arm 1) REBT, arm 2) VKD (NLP arm)Participants: adults meeting DSM-IV criteria for panic disorder age range 23–65 years. Recruited via media advert. Randomised n = 22, completed n = 18, (12 females/6 males) nine in each arm. Mean duration = 9.52 years. Follow-up numbersNLP interventionist: trained hypnotherapist (registered with UK Council for Psychotherapists as a hypno-psychotherapist) NLP Intervention: VKD also known as Fast Phobia technique. Four sessions at weekly intervalsHospital Anxiety and Depression Scale (HADS) Agoraphobic Cognitions Questionnaire (ACQ) Panic Attack Symptoms Questionnaire (PASQ) Global Panic Rating (GPR)Between groups: 4 week follow-up — no between group differences: HADS depression: F = 0.106, P = 0.749 HADS anxiety: F = 0.003, P = 0.96; ACQ: F = 0.374, P = 0.549; PASQ: F = 0.659, P = 0.429; GPR: F = 3.586, P = 0.076. There was a greater change in the pre-post scores for the VKD arm as follows pre-post intervention: GPR 18.78 reduced to 4.78; PASQ 74.78 reduced to 30.67; ACQ 2.37 reduced to 1.48; HADS anxiety 15.56 reduced to 7.11; HADS depression 9.67 reduced to 4.89
Pre-Post Study Design (uncontrolled)
Einspruch and Forman24 US PhobiaDesign: pre-post design. Setting: phobia and anxiety outpatient clinic. Assessment: baseline and 8 weeksParticipants: people with simple or multiple phobias. Mean age 44 years. Male 29%. Mostly college educated. Recruitment: not reported. Baseline and number completed not reported. Analysed n = 48: group, n = 31, individual n = 17. NB: Reports only those who completed both baseline and follow-up assessmentsNLP Interventionist training: not reported. NLP intervention: group or individual intervention according to assessed need. Individual: mean 2.8 sessions per person. Duration not stated. Group: weekly 2-hour sessions for 8 weeks plus three one-to-one sessionsMark’s Phobia questionnaire and Beck Depression Inventory16/17 individual participants and 27/29 group participants reported reduced phobia severity at follow-up (both P =<0.01). Group participants reported statistically significant improvements in depression scores (M=3.26; t = 5.18, P = <0.001), 27/29 reported reduced severity.
Timpany25 New Zealand Morning sickness in pregnancyDesign: pre-post. Setting: therapist office. Baseline and follow-up assessment. Follow-up time unreportedParticipants: women with moderate to severe morning sickness. Recruitment: press advert. Baseline n = 12, completed n =12 analysed n =12. Single 2-hour sessionNLP interventionist training: NLP trainer. NLP intervention: combination of NLP time line therapy, well-formed outcomes/goal setting and hypnotherapyPercentage of time feeling nauseous. Number of vomiting episodes per day. Stress (unreported measure)50% of women felt a significant reduction in symptoms in the week after the session. Four women went from feeling nauseous 100% of the time to 20% of the time and two women from 100% to 40%. 5/8 women who had been vomiting noted improvement
Konefal and Duncan26 Denmark Social anxietyDesign: pre-post. Setting: residential training course. Assessment: baseline (T0), post intervention (T1) and 6 months (T2)Participants: people with self-reported social anxiety. 15 male and 13 female), aged 20–60 years. Recruitment not reported. Baseline 28, completed = not reported, analysed n = 23NLP interventionist training: not stated NLP intervention: 15 skills and techniques detailed. Residential 21-day programmeLiebowitz Social Phobia ScaleSocial anxiety fear T0 M = 20.3 (SE 1.8); T1 M =12.9 (SE2.0); not reported, analysed n = 23 T2 M = 12.4 (SE1.7). Fear avoidance T0 = 20.1 (SE1.7), T1 = 14.5 (SE2.2), T2 = 14.0 (SE2.2). These findings were statistically different from T0 to T1 (P<0.001), but not statistically significant from T1 to T2
Gray27 US Substance misuseDesign: pre-post. Setting: community. Assessments: baseline and 16 weeksParticipants: substances mis-users. Recruitment: compulsory attendance. through criminal justice system. Baseline n = 127 of which 99 described as valid cases. Completed n = 80, analysed n = 99NLP interventionist training: not stated. NLP intervention: visualisation, anchoring, well-formed outcomes 2-hour weekly group session and two one-on-one sessions over 16 weeksUrinalysis for illegal substancesNon-significant difference between completers and non-completers. Abstinence after programme: completers = 55%; non-completers: 16%
Bigley et al 28 UK Claustrophobic patients undergoing MRIDesign: pre-post. Setting: NHS radiography department. Assessment: on day of NLP session and follow up on day of MRI prior to scan. Time lag unreportedParticipants: patients who had previously failed to undergo MRI. 24 males/26 females. Median age 52 years (range 17–75) Recruitment: NHS radiography department. Baseline n = 50, completed n = 50, analysed n = 50NLP interventionist training: MRI radiographer with NLP practitioner training. NLP intervention: ‘Clare’s fast phobia cure’: collapsing anchor, stacked anchor. Single session of 1 hour durationSuccessfully completed MRI. Anxiety measured by adapted Spielberger’s State-Trait Anxiety Inventory38 patients (76%) successfully completed MRI. A further nine (18%) went into the scanner but image was of insufficient quality. Anxiety scores significantly reduced after NLP in all participants, but no statistical difference between those completing MRI or not (P = 0.172). Cost saving of £319 per MRI examination of MRI with NLP vs MRI under general anaesthetic
  • NLP = neurolinguistic programming. OR = odds ratio. RCT = randomised controlled trial. REBT = rational emotive behaviour therapy. VKD = visual kinaesthetic dissociation.