Clinical characteristics of HIV cases and matched controls (THIN model)
| Cases | Controls | |||
|---|---|---|---|---|
| n | % | n | % | |
| Total n | 939 | 2576 | ||
| Males | 645 | 68.7 | 1771 | 68.8 |
| Mean age (standard deviation) | 41 | (11.4) | 42 | (11.0) |
| BHIVA conditionsa Bacterial pneumonia Aseptic meningitis/encephalitis Peripheral neuropathy | 17 2 2 | 1.8 0.2 0.2 | 1 0 1 | 0.0 0.0 0.0 |
| Seborrhoeic dermatitis 1 consultation only 2 consultations only 3+ consultations | 8 0 0 | 0.9 0.0 0.0 | 6 0 0 | 0.2 0.0 0.0 |
| Psoriasis 1 consultation only 2 consultations only 3+ consultations Herpes zoster Oral candidiasis Oral hairy leukoplakia | 8 7 2 32 35 3 | 0.9 0.8 0.2 3.4 3.7 0.3 | 9 4 1 4 2 0 | 0.4 0.2 0.0 0.2 0.1 0.0 |
| Diarrhoea 1 consultation only 2 consultations only 3+ consultations | 50 11 6 | 5.3 1.2 0.6 | 38 6 0 | 1.5 0.2 0.0 |
| Weight loss | 27 | 2.9 | 6 | 0.2 |
| Salmonella, shigella or campylobacter | 3 | 0.3 | 4 | 0.2 |
| Hepatitis B infection | 4 | 0.4 | 0 | 0.0 |
| Hepatitis C infection | 2 | 0.2 | 0 | 0.0 |
| Anal cancer/anal intraepithelial dysplasia | 1 | 0.1 | 0 | 0.0 |
| Seminoma | 0 | 0.0 | 1 | 0.0 |
| Non-Hodgkin’s lymphoma | 4 | 0.4 | 1 | 0.0 |
| Blood dyscrasia | 9 | 1.0 | 3 | 0.1 |
| Retinopathy in non-diabetic patient | 1 | 0.1 | 0 | 0.0 |
| Lymphadenopathy | 28 | 3.0 | 7 | 0.3 |
| Parotitis | 2 | 0.2 | 1 | 0.0 |
| Pyrexia of unknown origin | 17 | 1.8 | 7 | 0.3 |
| Any sexually transmitted infection | 15 | 1.6 | 3 | 0.1 |
| Number of indicator conditions per patient None of the indicator conditions One of the indicator conditions only Two or more indicator conditions | 697 195 47 | 74.2 20.8 5.0 | 2477 93 6 | 96.2 3.6 0.2 |
↵a There were no cases of aspergillosis, cerebral abscess, space-occupying lesion, Guillain–Barré syndrome, transverse myelitis, dementia, leukoencephalopathy, lung/head and neck cancer, Castleman’s disease, vaginal intraepithelial neoplasia, cervical intraepithelial neoplasia ≥grade 2, Infective retinal diseases, lymphoepithelial parotid cysts, or mononucleosis-like syndrome, in either case or control groups. BHIVA = British HIV Association.