Table 3

Stage 1: performance of items and their combinations identified to be significant through use of multiple logistic regression analysis

Condition at increased risk	Question number or combination	Sensitivity, % (n)	Specificity, % (n)
Diabetes	3	98 (112/114)	94 (461/493)

Heart disease	2	92 (74/80)	79 (425/536)

Breast cancer	8	73 (19/26)	84 (321/384)
	6	28 (7/25)	97 (374/385)
	8 and 6^a	92 (24/26)	81 (311/384)

Colorectal cancer	10	85 (11/13)	96 (573/600)
	11	54 (7/13)	89 (535/601)
	10 and 11^b	100 (13/13)	86 (515/599)

↵a Combination of questions 6 and 8 is significantly more predictive than question 8 (P < 0.001).
↵b Combination of questions 10 and 11 is non-significantly more predictive (P = 0.12) and retained for further assessment in stage 2.