Multilevel model of all-cause mortality and melanoma-specific mortality: reduced model based on the significance of factors in the first multivariate model
| All-cause mortality, HR (95% CI) | Melanoma-related mortality, HR (95% CI) | |||
|---|---|---|---|---|
| Primary modela | Secondary modela | Primary modela | Secondary modela | |
| Primary or secondary care | ||||
| Primary | 0.87 (0.66 to 1.14) | – | 0.95 (0.57 to 1.61) | – |
| Secondary | 1.00 | – | 1.00 | – |
| Speciality of submitter | ||||
| GP | 1.00 | 1.00 | ||
| GP frequent exciserb | – | 1.25 (0.69 to 2.26) | – | 0.46 (0.15 to 1.38) |
| Plastic surgeon | – | 1.14 (0.78 to 1.67) | – | 0.85 (0.43 to 1.70) |
| Dermatologist | – | 1.15 (0.72 to 1.84) | – | 1.00 (0.51 to 1.96) |
| Other specialist | – | 1.07 (0.74 to 1.54) | – | 0.46 (0.22 to 0.93) |
| Unknown | – | 0.83 (0.41 to 1.67) | – | 0.50 (0.19 to 1.32) |
| Age | 1.07 (1.05 to 1.08) | 1.07 (1.05 to 1.08) | 1.02 (1.01 to 1.03) | 1.02 (1.01 to 1.03) |
| Sex | ||||
| Male | 1.00 | 1.00 | 1.00 | 1.00 |
| Female | 0.66 (0.54 to 0.80) | 0.66 (0.54 to 0.80) | 0.46 (0.32 to 0.66) | 0.45 (0.31 to 0.66) |
| Place of residence | ||||
| Large urban area | 1.00 | 1.00 | 1.00 | 1.00 |
| Other urban area | 0.98 (0.71 to 1.35) | 0.98 (0.71 to 1.34) | 0.68 (0.37 to 1.26) | 0.71 (0.39 to 1.31) |
| Accessible small town | 0.86 (0.54 to 1.36) | 0.88 (0.57 to 1.37) | 0.75 (0.34 to 1.64) | 0.74 (0.32 to 1.69) |
| Remote small town | 1.04 (0.76 to 1.41) | 1.08 (0.77 to 1.53) | 1.08 (0.64 to 1.82) | 1.21 (0.72 to 2.02) |
| Accessible rural area | 0.83 (0.64 to 1.07) | 0.83 (0.64 to 1.08) | 0.82 (0.46 to 1.47) | 0.85 (0.49 to 1.47) |
| Remote rural area | 1.07 (0.72 to 1.58) | 1.08 (0.71 to 1.65) | 1.08 (0.60 to 1.97) | 1.11 (0.58 to 2.12) |
| 2009 SIMD quintile | ||||
| 1 most deprived | 1.64 (1.22 to 2.20) | 1.65 (1.23 to 2.22) | 1.93 (1.02 to 3.65) | 1.81 (0.93 to 3.53) |
| 2 | 1.03 (0.83 to 1.29) | 1.05 (0.84 to 1.32) | 0.98 (0.64 to 1.49) | 0.93 (0.60 to 1.46) |
| 3 | 1.03 (0.76 to 1.39) | 1.04 (0.77 to 1.41) | 1.07 (0.66 to 1.74) | 1.15 (0.70 to 1.89) |
| 4 | 0.99 (0.75 to 1.31) | 0.99 (0.75 to 1.31) | 0.80 (0.48 to 1.32) | 0.73 (0.44 to 1.21) |
| 5 least deprived | 1.00 | 1.0 | 1.00 | 1.00 |
| Anatomical site | ||||
| Head and neck | 1.26 (0.89 to 1.79) | 1.26 (0.90 to 1.76) | 1.00 (0.68 to 1.48) | 0.96 (0.65 to 1.40) |
| Body | 1.18 (0.84 to 1.66) | 1.16 (0.81 to 1.66) | 1.12 (0.65 to 1.95) | 1.13 (0.64 to 2.02) |
| Upper limb | 0.95 (0.71 to 1.26) | 0.95 (0.72 to 1.26) | 0.85 (0.50 to 1.46) | 0.77 (0.44 to 1.35) |
| Groins | 2.14 (0.99 to 4.64) | 2.68 (1.15 to 6.22) | 3.31 (1.08 to 10.10) | 3.84 (1.01 to 14.68) |
| Lower limb | 1.00 | 1.00 | 1.00 | 1.00 |
| Not stated | 0.85 (0.44 to 1.64) | 0.86 (0.44 to 1.67) | 0.86 (0.29 to 2.53) | 0.82 (0.26 to 2.58) |
| Melanoma type | ||||
| Superficial spreading | 1.00 | 1.00 | 1.00 | 1.00 |
| Nodular | 1.09 (0.84 to 1.40) | 1.10 (0.86 to 1.39) | 1.36 (0.81 to 2.28) | 1.45 (0.91 to 2.30) |
| Lentigo maligna | 0.96 (0.75 to 1.24) | 0.96 ((0.75 to 1.24) | 0.96 (0.43 to 2.16) | 0.94 (0.43 to 2.07) |
| Acral | 1.25 (0.78 to 2.01) | 1.27 (0.79 to 2.05) | 2.17 (1.23 to 3.83) | 2.24 (1.29 to 3.91) |
| Other | 1.21 (0.76 to 1.93) | 1.23 (0.78 to 1.95) | 1.59 (0.61 to 4.13) | 1.60 (0.63 to 4.10) |
| Not stated | 1.02 (0.61 to 1.70) | 1.02 (0.62 to 1.68) | 0.78 (0.25 to 2.43) | 0.86 (0.29 to 2.52) |
| Clark level | ||||
| I | 1.00 | 1.00 | 1.00 | 1.00 |
| II | 1.32 (0.80 to 2.19) | 1.31 (0.79 to 2.17) | 2.05 (0.64 to 6.62) | 2.05 (0.63 to 6.64) |
| III | 1.48 (0.91 to 2.41) | 1.47 (0.90 to 2.40) | 2.76 (0.86 to 8.84) | 2.97 (0.94 to 9.42) |
| IV | 2.50 (1.53 to 4.08) | 2.45 (1.50 to 4.00) | 7.26 (2.45 to 21.49) | 7.68 (2.57 to 22.89) |
| V | 3.56 (1.97 to 6.44) | 3.51 (1.97 to 6.24) | 13.33 (3.58 to 49.67) | 13.78 (3.97 to 47.91) |
| Not stated | 2.52 (1.38 to 4.59) | 2.56 (1.37 to 4.76) | 6.12 (2.06 to 18.20) | 5.85 (1.94 to 17.68) |
| Breslow depth | 1.05 (1.00 to 1.09) | 1.05 (1.01 to 1.09) | 1.10 (1.05 to 1.16) | 1.11 (1.06 to 1.17) |