Incidence rates of appetite loss, weight loss, abdominal pain, abdominal distension, and dysphagia per 100 000 person-years by sex and age in the THIN cohort
| Symptom and age range, years | Incidence rate (95% CI) | |
|---|---|---|
| Females | Males | |
| Appetite loss | ||
| All ages | 52.0 (50.3 to 53.8) | 41.5 (39.9 to 43.1) |
| <35 | 15.5 (12.9 to 18.6) | 10.8 (8.7 to 13.4) |
| 35–44 | 25.0 (22.6 to 27.5) | 17.6 (15.7 to 19.7) |
| 45–54 | 26.3 (23.7 to 29.1) | 21.4 (19.1 to 23.8) |
| 55–64 | 35.5 (32.2 to 39.1) | 34.2 (31.0 to 37.8) |
| 65–74 | 84.9 (79.1 to 91.1) | 85.1 (78.8 to 91.7) |
| 75–84 | 205.1 (194.2 to 216.4) | 207.8 (194.2 to 222.1) |
| Weight loss | ||
| All ages | 241.5 (237.7 to 245.2) | 210.6 (207.0 to 214.2) |
| <35 | 87.9 (81.4 to 94.9) | 55.1 (50.1 to 60.4) |
| 35–44 | 150.1 (144.3 to 156.2) | 108.9 (104.1 to 114.0) |
| 45–54 | 171.2 (164.6 to 178.1) | 142.4 (136.4 to 148.6) |
| 55–64 | 222.1 (213.7 to 230.8) | 232.7 (224.1 to 241.6) |
| 65–74 | 344.9 (333.0 to 357.1) | 383.5 (370.1 to 397.3) |
| 75–84 | 700.0 (679.8 to 720.7) | 779.0 (752.4 to 806.2) |
| Abdominal pain | ||
| All ages | 2240.8 (2229.4 to 2252.2) | 1667.4 (1657.4 to 1677.4) |
| <35 | 1901.6 (1870.7 to 1932.8) | 877.8 (857.5 to 898.4) |
| 35–44 | 2452.2 (2428.4 to 2476.2) | 1542.3 (1523.8 to 1560.9) |
| 45–54 | 2103.3 (2079.7 to 2127.1) | 1560.9 (1540.8 to 1581.2) |
| 55–64 | 2300.2 (2273.1 to 2327.7) | 1885.2 (1860.4 to 1910.2) |
| 65–74 | 2253.8 (2223.2 to 2284.7) | 2165.0 (2132.9 to 2197.4) |
| 75–84 | 2275.0 (2238.4 to 2312.0) | 2529.4 (2481.4 to 2578.1) |
| Abdominal distension | ||
| All ages | 67.3 (65.4 to 69.4) | 31.2 (29.9 to 32.6) |
| <35 | 29.6 (25.9 to 33.8) | 5.9 (4.4 to 7.8) |
| 35–44 | 52.7 (49.3 to 56.4) | 15.3 (13.5 to 17.3) |
| 45–54 | 60.8 (56.9 to 65.0) | 25.5 (23.0 to 28.2) |
| 55–64 | 71.8 (67.1 to 76.8) | 36.4 (33.0 to 40.0) |
| 65–74 | 91.3 (85.3 to 97.7) | 62.2 (56.9 to 67.9) |
| 75–84 | 121.2 (112.9 to 130.0) | 92.2 (83.2 to 101.8) |
| Dysphagia | ||
| All ages | 163.6 (160.5 to 166.7) | 145.6 (142.7 to 148.6) |
| <35 | 30.4 (26.6 to 34.6) | 27.0 (23.5 to 30.8) |
| 35–44 | 80.5 (76.3 to 85.0) | 66.0 (62.2 to 70.0) |
| 45–54 | 133.1 (127.2 to 139.2) | 104.7 (99.5 to 111.0) |
| 55–64 | 189.5 (181.8 to 197.5) | 182.8 (175.1 to 190.7) |
| 65–74 | 252.5 (242.3 to 263.0) | 279.1 (267.7 to 290.9) |
| 75–84 | 426.4 (410.6 to 442.5) | 489.3 (468.3 to 511.0) |