Individual risk factors within high-risk patients in the source population and in the high-risk sample
| Risk factora | Number of high-risk patients | |
|---|---|---|
| Source population n = 5550, n (%) | High-risk sample n = 819, n (%) | |
| History of peptic ulcer/UGI complication | 428 (8) | 184 (22) |
| Age >70 years | 3662 (66) | 390 (48) |
| Two or more minor UGI risk factorsb | 1711 (31) | 410 (50) |
| History of myocardial infarction | 686 (12) | 152 (19) |
| History of stroke | 504 (9) | 108 (13) |
| Heart failure | 214 (4) | 156 (19) |
| Chronic renal insufficiency (GFR <30 mL/min) | 69 (1) | 60 (7) |
GFR: glomerular filtration rate. UGI = upper gastrointestinal.
↵a Risk factors can overlap.
↵b Two or more of the following minor risk factors: use of anticoagulant, use of aspirin, use of corticosteroid, use of selective serotonin reuptake inhibitor, age 60–70 years, history of severe rheumatoid arthritis, diabetes mellitus, or heart failure.